ea0081p395 | Environmental Endocrinology | ECE2022
Maria Bimonte Viviana
, Sabato Claudia
, Trocchianesi Sofia
, Mersini Besharat Zein
, Po Agnese
, catanzaro giuseppina
, Falcone Italia
, Fabi Alessandra
, Bei Roberto
, Milella Michele
, Vacca Alessandra
, Ferretti Elisabetta
, Migliaccio Silvia
The highly toxic heavy metal Cadmium (Cd) is widely spread in the environment and could exert estrogen-like activity in tissues including breast. Previous studies demonstrated that Cd binds to estrogen receptor α positive (ERα+) breast cancer (BC) cells. In this new study, we evaluated effects of Cd on both ERα+ and ERα negative (ERα-) BC models with the aim to further characterize the mechanisms involved in Cd-related BC carcinogenesis. Specifically, ...